What is defined as an adverse drug event (ADE)?

An adverse drug event (ADE) is specifically defined as an injury resulting from medical intervention related to a drug. This definition encompasses a range of possible issues, including medication errors, adverse reactions, and complications from appropriate uses of a medication. It highlights that the complete context of how a drug is administered and monitored is critical when assessing its safety and efficacy.

This definition is broader than simply a side effect or an allergic reaction, which are specific types of responses to medications. Side effects can occur with many medications and are often expected or known. An allergic reaction is a unique subset of side effects that involve the immune system and is typically noted during the drug's development. Both of these responses may be unpleasant or harmful, but they do not encompass the entirety of what an ADE might involve.

Moreover, a negative review of a medication reflects public opinion or a subjective assessment rather than a clinical categorization of harm caused by the medication itself. Thus, focusing on the comprehensive nature of ADEs as linked to medical interventions provides clarity and supports a better understanding of medication safety practices.